Long-lasting hyperpolarization underlies seizure reduction by low frequency deep brain electrical stimulation
نویسندگان
چکیده
منابع مشابه
Control of epileptic seizures by electrical low frequency deep brain stimulation: A review of probable mechanisms
Epilepsy is the most common neurological disease with no definitive method in treatment. Notably, the main way to treat and control epileptic seizures is drug therapy. However, about 20-30% of patients with epilepsy are drug resistant and require other therapeutic manners. Deep brain stimulation is a new therapeutic strategy for these patients. Conspicuously, there are no clear answers for basi...
متن کاملIncreasing the Effectiveness of Carbamazepine by Low Frequency Electrical Stimulation During CA1 Hippocampal Kindling on Seizure Scales in Adult Male Rats: An Experimental Study
Background and Objectives Nowadays, the application of Low Frequency Stimulations (LFS) has been considered as an alternative treatment in drug-resistant epileptic patients. So, the aim of this study was to determine the co-administration effects of LFS and carbamazepine (CBZ) during epileptogenesis in dorsal hippocampus using electrical Kindling method on seizure scales in adult male rats. ...
متن کاملO10: Deep Brain Stimulation and Psychiatry
The use of deep brain stimulation in psychiatric disorders has received great interest owing to the small risk of the operation, the reversible nature of the technique, and the possibility of optimizing treatment postoperatively. Currently deep brain stimulation in psychiatry is investigated for obsessive-compulsive disorder, Gilles de la Tourette’s syndrome and major depression. This presentat...
متن کاملThe Therapeutic Effects of Low-Frequency Electrical Stimulations Adjunct to Sodium Valproate on Seizure and Behaviors
Introduction: Consuming antidepressant medications induce several problems leading to the need for alternative agents for emotional disturbances. Antidepressant medications increase the seizure risk; thus, alternative treatments, like Antiepileptic Drugs (AED), might be useful for patients with epilepsy comorbid with a psychiatric disorder. The present study evaluated the behavioral effects of ...
متن کاملLOW VOLTAGE ELECTRICAL STIMULATION AND WOUND HEALING IN RABBITS: EFFECT OF ALTERING FREQUENCY
The effect of electrical currents by different modalities on wound healing has been experimented. In this study a survey of the literature shows different results, and the mechanisms of action have not been elucidated for certain. The aim of this study was to compare the results obtained from low voltage-square wave stimulation of different frequencies. Results show that the healing period ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 2013
ISSN: 0022-3751
DOI: 10.1113/jphysiol.2013.253757